A SIMPLE KEY FOR CONOLIDINE UNVEILED

These effects, together with a previous report showing that a small-molecule ACKR3 agonist CCX771 exhibits anxiolytic-like conduct in mice,two help the strategy of focusing on ACKR3 as a singular technique to modulate the opioid system, which could open new therapeutic avenues for opioid-associated disorders.These results counsel that conolidine is